Narra la historia de dos coaliciones - ACT UP y TAG cuyo activismo y la innovación convertió el Sida de una sentencia de muerte a una condición manejable.
 | David Barrass | Himself |
| Bill Bahlman | Himself |
| Gregg Bordowitz | Himself |
| George Bush | Himself |
| Bill Clinton | Himself |
| Jim Eigo | Himself |
| Mark Harrington | Himself |
| Larry Kramer | Himself |
| Iris Long | Herself |
| Ray Navarro | Himself |
| Bob Rafsky | Himself |
| Peter Staley | Himself |
