Gira en torno a un cuarteto de cuerda que prepara un concierto para celebrar su 25 aniversario, cuando a uno de ellos le diagnostican Parkinson.
 | Christopher Walken | Peter Mitchell |
 | Philip Seymour Hoffman | Robert Gelbart |
 | Imogen Poots | Alexandra Gelbart |
 | Catherine Keener | Juliette Gelbart |
| Wallace Shawn | Gideon Rosen |
| Mark Ivanir | Daniel Lerner |
| Madhur Jaffrey | Dr. Nadir |
| Liraz Charhi | Pilar |
| Marty Krzywonos | Cab Driver |
| Megan McQuillan | Brenda |
| Anne Sofie von Otter | Miriam |
| Jasmine Hope Bloch | Cello Student |
| Rebeca Tomas | Flamenco dancer |
| Nina Lee | Nina Lee |
| Cristian Puig | Flamenco singer |
