Comedia de múltiples historias sobre las distintas experiencias de varias parejas durante el embarazo.
 | Elizabeth Banks | Wendy |
 | Cameron Diaz | Jules |
 | Jennifer Lopez | Holly |
 | Anna Kendrick | Rosie |
 | Dennis Quaid | Ramsey |
 | Chris Rock | Vic |
| Brooklyn Decker | Skyler |
 | Rodrigo Santoro | Nate |
| Chace Crawford | Marco |
| Joe Manganiello | Davis |
 | Thomas Lennon | Craig |
| Rebel Wilson | Janice |
| Genesis Rodriguez | Courtney |
| Wendi McLendon-Covey | Kara |
| Ben Falcone | Gary |
| Rob Huebel | Gabe |
| Megan Mullally | Megan Mullally |
| Matthew Morrison | Evan |
| Amir Talai | Patel |
| Dwyane Wade | Dwyane Wade |
| Whitney Port | Whitney Port |
| Cheryl Cole | Cheryl Cole |
