Christopher Jones, un capitán, se dispone a dirigir su barco de pasajeros a su destino, el Nuevo Mundo, contra viento y marea.
 | Spencer Tracy | Capitán Christopher Jones |
| Gene Tierney | Dorothy Bradford |
| Van Johnson | John Alden |
| Leo Genn | William Bradford |
| Barry Jones | William Brewster |
| Dawn Addams | Priscilla Mullins |
| Lloyd Bridges | Coppin |
| Noel Drayton | Miles Standish |
| John Dehner | Gilbert Winslow |
| Tommy Ivo | William Button |
| Lowell Gilmore | Edward Winslow |
| The Mayflower | |
| Rhys Williams | Mr. Weston; no acreditado |
